Search on: LIGASES 
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Descriptor English:   Ligases 
Descriptor Spanish:   Ligasas 
Descriptor Portuguese:   Ligases 
Synonyms English:   Synthetase
Tree Number:   D08.811.464
Definition English:   A class of enzymes that catalyze the formation of a bond between two substrate molecules, coupled with the hydrolysis of a pyrophosphate bond in ATP or a similar energy donor. (Dorland, 28th ed) EC 6. 
History Note English:   CARBOXYLASES was see under CARBOXY-LYASES & LIGASES 1964-74, was heading 1963 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   8201 
Unique Identifier:   D008025 

Occurrence in VHL: