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Descriptor English: Mefruside
Descriptor Spanish: Mefrusida
Descriptor mefrusida
Scope note: Benceno-sulfonaminda-furano. Diurético que afecta a la capacidad de concentración del RIÑÓN, aumenta la excreción de CLORURO SÓDICO, pero no economiza POTASIO. Inhibe las ANHIDRASAS CARBÓNICAS y puede aumentar los niveles de ÁCIDO ÚRICO en la sangre.
Descriptor Portuguese: Mefrusida
Descriptor French: Méfruside
Tree number(s): D02.065.884.575
D02.886.590.700.575
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008529
Scope note: A benzene-sulfonamide-furan. It is used as a diuretic that affects the concentrating ability of the KIDNEY, increases SODIUM CHLORIDE excretion, but may not spare POTASSIUM. It inhibits CARBONIC ANHYDRASES and may increase the blood URIC ACID level.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Diuretics
Registry Number: X1NS9SNS92
CAS Type 1 Name: 1,3-Benzenedisulfonamide, 4-chloro-N1-methyl-N1-((tetrahydro-2-methyl-2-furanyl)methyl)-
Previous Indexing: Diuretics, Sulfamyl (1974-1975)
Furans (1972-1975)
Public MeSH Note: 91; was see under DIURETICS, SULFAMYL 1976-90
History Note: 91(76); was see under DIURETICS, SULFAMYL 1976-90
DeCS ID: 8697
Unique ID: D008529
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1975/07/23
Revision Date: 2013/07/08
Mefruside - Preferred
Concept UI M0013288
Scope note A benzene-sulfonamide-furan. It is used as a diuretic that affects the concentrating ability of the KIDNEY, increases SODIUM CHLORIDE excretion, but may not spare POTASSIUM. It inhibits CARBONIC ANHYDRASES and may increase the blood URIC ACID level.
Preferred term Mefruside



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