Search on: MERCAPTOPURINE 
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Descriptor English:   Mercaptopurine 
Descriptor Spanish:   Mercaptopurina 
Descriptor Portuguese:   Mercaptopurina 
Synonyms English:   1,7-Dihydro-6H-purine-6-thione
6 Mercaptopurine
6 Mercaptopurine Monohydrate
6 Thiohypoxanthine
6 Thiopurine
6-Mercaptopurine
6-Mercaptopurine Monohydrate
6-Thiohypoxanthine
6-Thiopurine
6H-Purine-6-thione, 1,7-dihydro-
BW 57 323H
BW 57-323H
BW 57323H
Leupurin
Mecaptopurine Anhydrous
Mercaptopurina Wellcome
Puri-Nethol
Purimethol
Purinethol  
Tree Number:   D02.886.489.534
D03.633.100.759.570
Definition English:   An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia. 
Pharmacological Action:   Antimetabolites
Antimetabolites, Antineoplastic
Immunosuppressive Agents
Nucleic Acid Synthesis Inhibitors
 
History Note English:   2018(1985) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   8800 
Unique Identifier:   D015122 

Occurrence in VHL:
 
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MEDLINE    
MedCarib    
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