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Descriptor English: Metformin
Descriptor Spanish: Metformina
Descriptor metformina
Entry term(s) dimetilguanilguanidina
Scope note: Agente hipoglucemiante biguanídico utilizado en el tratamiento de la diabetes mellitus no insulinodependiente que no responde a modificaciones de la dieta. La metformina mejora el control glucémico al mejorar la sensibilidad a la insulina y disminuir la absorción intestinal de glucosa. (Martindale, The Extra Pharmacopoeia, 30th ed, p289).
Descriptor Portuguese: Metformina
Descriptor French: Metformine
Entry term(s): Dimethylbiguanidine
Dimethylguanylguanidine
Glucophage
HCl, Metformin
Hydrochloride, Metformin
Metformin HCl
Metformin Hydrochloride
Tree number(s): D02.078.370.141.450
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008687
Scope note: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
Annotation: a hypoglycemic
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Hypoglycemic Agents
Registry Number: 9100L32L2N
CAS Type 1 Name: Imidodicarbonimidic diamide, N,N-dimethyl-
DeCS ID: 8862
Unique ID: D008687
NLM Classification: WK 825
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2015/05/26
Metformin - Preferred
Concept UI M0013535
Scope note A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
Preferred term Metformin
Entry term(s) Dimethylbiguanidine
Dimethylguanylguanidine
Glucophage - Narrower
Concept UI M0013536
Preferred term Glucophage
Metformin Hydrochloride - Narrower
Concept UI M000604093
Preferred term Metformin Hydrochloride
Entry term(s) HCl, Metformin
Hydrochloride, Metformin
Metformin HCl



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