Search on: METFORMIN 
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Descriptor English:   Metformin 
Descriptor Spanish:   Metformina 
Descriptor Portuguese:   Metformina 
Synonyms English:   Dimethylbiguanidine
Dimethylguanylguanidine
Glucophage
HCl, Metformin
Hydrochloride, Metformin
Metformin HCl
Metformin Hydrochloride  
Tree Number:   D02.078.370.141.450
Definition English:   A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289) 
Indexing Annotation English:   a hypoglycemic
Pharmacological Action:   Hypoglycemic Agents
 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   8862 
Unique Identifier:   D008687 

Occurrence in VHL:
 
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MEDLINE    
BDENF    
MedCarib    
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