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Descriptor English: Methimazole
Descriptor Spanish: Metimazol
Descriptor metimazol
Entry term(s) tiamazol
Scope note: Tioureileno, agente antitiroideo que inhibe la formación de hormonas tiroideas al interferir en la incorporación de iodo en los residuos tirosilo de la tiroglobulina. Esto se realiza interfiriendo con la oxidación del ión ioduro y grupos iodotirosilos mediante la inhibición de la enzima peroxidasa.
Descriptor Portuguese: Metimazol
Descriptor French: Thiamazol
Entry term(s): 1 Methyl 2 mercaptoimidazole
1-Methyl-2-mercaptoimidazole
Favistan
Henning, Thiamazol
Hexal, Thiamazol
Mercasolyl
Mercazol
Mercazole
Mercazolyl
Merkazolil
Methizol
Methylmercaptoimidazole
Methymazol
Metisol
Metizol
Strumazol
Tapazole
Thiamazol Henning
Thiamazol Hexal
Thiamazole
Thimazol
Thyrozol
Tiamazol
Tirodril
Tree number(s): D02.886.489.600
D03.383.129.308.535
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008713
Scope note: A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antithyroid Agents
Registry Number: 554Z48XN5E
CAS Type 1 Name: 2H-Imidazole-2-thione, 1,3-dihydro-1-methyl-
Previous Indexing: Imidazoles (1966-1967)
Thyroid Antagonists (1966-1967)
Public MeSH Note: 73; was see under THYROID ANTAGONISTS 1963-72
Online Note: search THYROID ANTAGONISTS 1966-67
History Note: 73(68); was see under THYROID ANTAGONISTS 1963-72
DeCS ID: 8890
Unique ID: D008713
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24
Methimazole - Preferred
Concept UI M0013573
Scope note A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.
Preferred term Methimazole
Entry term(s) 1 Methyl 2 mercaptoimidazole
1-Methyl-2-mercaptoimidazole
Mercasolyl
Mercazolyl
Merkazolil
Methylmercaptoimidazole
Methymazol
Thiamazole
Thimazol
Tiamazol
Mercazol - Narrower
Concept UI M0352357
Preferred term Mercazol
Entry term(s) Mercazole
Metisol - Narrower
Concept UI M0352356
Preferred term Metisol
Entry term(s) Metizol
Tapazole - Narrower
Concept UI M0352355
Preferred term Tapazole
Tirodril - Narrower
Concept UI M0476439
Preferred term Tirodril
Strumazol - Narrower
Concept UI M0476435
Preferred term Strumazol
Thiamazol Henning - Narrower
Concept UI M0476436
Preferred term Thiamazol Henning
Entry term(s) Henning, Thiamazol
Thiamazol Hexal - Narrower
Concept UI M0476437
Preferred term Thiamazol Hexal
Entry term(s) Hexal, Thiamazol
Thyrozol - Narrower
Concept UI M0476438
Preferred term Thyrozol
Favistan - Narrower
Concept UI M0352358
Preferred term Favistan
Methizol - Narrower
Concept UI M0476434
Preferred term Methizol



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