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Descriptor English: Metolazone
Descriptor Spanish: Metolazona
Descriptor metolazona
Scope note: Diurético derivado de la quinazolina-sulfonamida que actúa inhibiendo los SIMPORTADORES SODIO CLORO.
Descriptor Portuguese: Metolazona
Descriptor French: Métolazone
Entry term(s): Diulo
Microx
Mykrox
SR 720 22
SR-720-22
SR72022
Zaroxolyn
Tree number(s): D02.065.884.600
D02.886.590.700.600
D03.633.100.786.830.688
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008788
Scope note: A quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antihypertensive Agents
Diuretics
Sodium Chloride Symporter Inhibitors
Registry Number: TZ7V40X7VX
CAS Type 1 Name: 6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-
Previous Indexing: Diuretics, Sulfamyl (1974)
Quinazolines (1971-1974)
Public MeSH Note: 91; was see under DIURETICS, SULFAMYL 1975-90
History Note: 91(75); was see under DIURETICS, SULFAMYL 1975-90
DeCS ID: 8978
Unique ID: D008788
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/11
Revision Date: 2017/05/24
Metolazone - Preferred
Concept UI M0013684
Scope note A quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
Preferred term Metolazone
Microx - Narrower
Concept UI M0350908
Preferred term Microx
Entry term(s) Mykrox
Zaroxolyn - Narrower
Concept UI M0350906
Preferred term Zaroxolyn
Diulo - Narrower
Concept UI M0350909
Preferred term Diulo
SR-720-22 - Narrower
Concept UI M0350907
Preferred term SR-720-22
Entry term(s) SR 720 22
SR72022



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