Search on: MITOCHONDRIAL UNCOUPLING PROTEINS 
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Descriptor English:   Mitochondrial Uncoupling Proteins 
Descriptor Spanish:   Proteínas Desacopladoras Mitocondriales 
Descriptor Portuguese:   Proteínas de Desacoplamento Mitocondrial 
Synonyms English:   Mitochondrial UCPs
UCPs, Mitochondrial
Uncoupling Proteins
Uncoupling Proteins, Mitochondrial  
Tree Number:   D12.776.157.530.937.598
D12.776.543.585.475.688
D12.776.543.585.937.696
D12.776.575.750.688
Definition English:   Mitochondrial anion carrier proteins that function as dimers and form proton channels in the INNER MITOCHONDRIAL MEMBRANE which creates proton leaks and uncouples OXIDATIVE PHOSPHORYLATION from ATP synthesis, resulting in the generation of heat instead of ATP. 
History Note English:   2017 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   56587 
Unique Identifier:   D000071245 

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