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Descriptor English: Mitomycin
Descriptor Spanish: Mitomicina
Descriptor mitomicina
Entry term(s) mitomicina C
Scope note: Antibiótico antineoplásico producido por Streptomyces caespitosus. Es uno de los AGENTES ALQUILANTES bi o trifuncionales que causan entrecruzamiento del ADN e inhibición de la síntesis del ADN.
Descriptor Portuguese: Mitomicina
Descriptor French: Mitomycine
Entry term(s): Ametycine
Mitocin C
Mitocin-C
MitocinC
Mitomycin C
Mitomycin-C
Mutamycin
NSC 26980
NSC-26980
NSC26980
Tree number(s): D02.806.400.249.350
D03.383.097.500.350
D03.633.100.473.412.249.350
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016685
Scope note: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
Annotation: MITOMYCINS is also available
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Entry Combination: analogs & derivatives:Mitomycins
Pharm Action: Alkylating Agents
Antibiotics, Antineoplastic
Cross-Linking Reagents
Nucleic Acid Synthesis Inhibitors
Registry Number: 50SG953SK6
CAS Type 1 Name: Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS-(1aalpha,8beta,8aalpha,8balpha))-
Previous Indexing: Mitomycins (1966-1991)
Public MeSH Note: 2000(1992); see MITOMYCIN C 1992-1999; MITOMYCIN C was indexed under MITOMYCINS 1981-1990
History Note: 2000(1992); for MITOMYCIN use MITOMYCIN (NM) 1981-1991
DeCS ID: 29961
Unique ID: D016685
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1992/01/01
Date of Entry: 1991/01/25
Revision Date: 2016/05/31
Mitomycin - Preferred
Concept UI M0013948
Scope note An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
Preferred term Mitomycin
Entry term(s) Mitomycin C
Mitomycin-C
Mitocin-C - Narrower
Concept UI M0353143
Preferred term Mitocin-C
Entry term(s) Mitocin C
MitocinC
NSC-26980 - Narrower
Concept UI M0353141
Preferred term NSC-26980
Entry term(s) NSC 26980
NSC26980
Ametycine - Narrower
Concept UI M0353144
Preferred term Ametycine
Mutamycin - Narrower
Concept UI M0353142
Preferred term Mutamycin



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