Search on: MUSCIMOL 
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Descriptor English:   Muscimol 
Descriptor Spanish:   Muscimol 
Descriptor Portuguese:   Muscimol 
Synonyms English:   Agarin
Pantherine  
Tree Number:   D03.383.129.462.470
D23.946.587.587
Definition English:   A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies. 
Pharmacological Action:   GABA-A Receptor Agonists
 
See Related English:   Receptors, GABA-A
 
History Note English:   86(79); was see under OXAZOLES 1979-85 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   9308 
Unique Identifier:   D009118 

Occurrence in VHL:
 
LILACS    
MEDLINE    
BBO    
IBECS    

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