Search on: MUSTARD COMPOUNDS 
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Descriptor English:   Mustard Compounds 
Descriptor Spanish:   Compuestos de Mostaza 
Descriptor Portuguese:   Compostos de Mostarda 
Synonyms English:   Compounds, Mustard  
Tree Number:   D02.455.526.728
Definition English:   Strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis(2-chloroethyl)- groups. Although otherwise structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA. They are generally highly toxic but include among their number many widely used and effective antineoplastic agents. 
History Note English:   68 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   21038 
Unique Identifier:   D009150 

Occurrence in VHL:
 
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