Search on: MYOSINS 
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Descriptor English:   Myosins 
Descriptor Spanish:   Miosinas 
Descriptor Portuguese:   Miosinas 
Synonyms English:   ATPase, Actin Activated
ATPase, Actin-Activated
ATPase, Actomyosin
ATPase, Myosin
Actin Activated ATPase
Actin-Activated ATPase
Actomyosin ATPase
Actomyosin Adenosinetriphosphatase
Adenosine Triphosphatase, Myosin
Adenosinetriphosphatase, Actomyosin
Adenosinetriphosphatase, Myosin
Myosin
Myosin ATPase
Myosin Adenosine Triphosphatase
Myosin Adenosinetriphosphatase  
Tree Number:   D05.750.078.730.475
D08.811.277.040.025.193.750
D12.776.210.500.600
D12.776.220.525.475
Definition English:   A diverse superfamily of proteins that function as translocating proteins. They share the common characteristics of being able to bind ACTINS and hydrolyze MgATP. Myosins generally consist of heavy chains which are involved in locomotion, and light chains which are involved in regulation. Within the structure of myosin heavy chain are three domains: the head, the neck and the tail. The head region of the heavy chain contains the actin binding domain and MgATPase domain which provides energy for locomotion. The neck region is involved in binding the light-chains. The tail region provides the anchoring point that maintains the position of the heavy chain. The superfamily of myosins is organized into structural classes based upon the type and arrangement of the subunits they contain. 
Indexing Annotation English:   GEN or unspecified; prefer specifics
History Note English:   2002(1971); use ADENOSINE TRIPHOSPHATASE 1963-1968; for MYOSIN ATPASE use ADENOSINETRIPHOSPHATASE 1984-1988; for ACTOMYOSIN ATPASE use ADENOSINETRIPHOSPHATASE 1985-1988 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   29449 
Unique Identifier:   D009218 

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