Search on: NITROGEN MUSTARD COMPOUNDS 
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Descriptor English:   Nitrogen Mustard Compounds 
Descriptor Spanish:   Compuestos de Mostaza Nitrogenada 
Descriptor Portuguese:   Compostos de Mostarda Nitrogenada 
Synonyms English:   Compounds, Nitrogen Mustard
Mustard Compounds, Nitrogen  
Tree Number:   D02.455.526.728.650
Definition English:   A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens. 
Indexing Annotation English:   do not confuse with NITROGEN MUSTARD, a specific chemical
Pharmacological Action:   Antineoplastic Agents, Alkylating
 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   9773 
Unique Identifier:   D009588 

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