Search on: PHENOBARBITAL 
Descriptors Found: 1
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Descriptor English:   Phenobarbital 
Descriptor Spanish:   Fenobarbital 
Descriptor Portuguese:   Fenobarbital 
Synonyms English:   Acid, Phenylethylbarbituric
Gardenal
Hysteps
Luminal
Monosodium Salt Phenobarbital
Phenemal
Phenobarbital Sodium
Phenobarbital, Monosodium Salt
Phenobarbitone
Phenylbarbital
Phenylethylbarbituric Acid
Sodium, Phenobarbital  
Tree Number:   D03.383.742.698.253.650
Definition English:   A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations. 
Pharmacological Action:   Anticonvulsants
Hypnotics and Sedatives
Excitatory Amino Acid Antagonists
GABA Modulators
Cytochrome P-450 CYP2B6 Inducers
Cytochrome P-450 CYP3A Inducers
 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   10826 
Unique Identifier:   D010634 

Occurrence in VHL:
 
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MEDLINE    
BDENF    
HomeoIndex    
MedCarib    
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