Descriptors Found: 1
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Descriptor English:   Phospholipases A2, Secretory 
Descriptor Spanish:   Fosfolipasas A2 Secretoras 
Descriptor Portuguese:   Fosfolipases A2 Secretórias 
Synonyms English:   Phospholipase A2, Secretory
Phospholipases A2, Secreted
Phospholipases, SPLA2
SPLA2 Phospholipases
Secreted Phospholipases A2
Secretory Phospholipase A2
Secretory Phospholipases A2
Tree Number:   D08.811.277.352.100.680.750.937.750
Definition English:   A subcategory of phospholipases A2 that are secreted from cells. They are 14 kDa proteins containing multiple disulfide-bonds and access their substrate via an interfacial binding site that interacts with phospholipid membranes. In addition specific PHOSPHOLIPASE A2 RECEPTORS can bind to and internalize the enzymes. 
Indexing Annotation English:   /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS
History Note English:   2008 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52667 
Unique Identifier:   D054497 

Occurrence in VHL: