Search on: PINACIDIL 
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Descriptor English:   Pinacidil 
Descriptor Spanish:   Pinacidilo 
Descriptor Portuguese:   Pinacidil 
Synonyms English:   Anhydrous, Pinacidil
Pinacidil Anhydrous
Tree Number:   D02.078.370.729
Definition English:   A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed) 
Pharmacological Action:   Antihypertensive Agents
Vasodilator Agents
Membrane Transport Modulators
History Note English:   99; use PINACIDIL (NM) 1980-98 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   33787 
Unique Identifier:   D020110 

Occurrence in VHL: