Search on: PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE 
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Descriptor English:   Pituitary Adenylate Cyclase-Activating Polypeptide 
Descriptor Spanish:   Polipéptido Hipofisario Activador de la Adenilato-Ciclasa 
Descriptor Portuguese:   Polipeptídeo Hipofisário Ativador de Adenilato Ciclase 
Synonyms English:   PACAP
PACAP-27
PACAP-38
PACAP27
PACAP38
Pituitary Adenylate Cyclase Activating Polypeptide
Pituitary Adenylate Cyclase Activating Polypeptide 27
Pituitary Adenylate Cyclase Activating Polypeptide 38  
Tree Number:   D12.644.276.860.887
D12.644.400.625
D12.776.467.860.887
D12.776.631.600.887
D12.776.631.650.625
D23.529.850.887
Definition English:   A multi-function neuropeptide that acts throughout the body by elevating intracellular cyclic AMP level via its interaction with PACAP RECEPTORS. Although first isolated from hypothalamic extracts and named for its action on the pituitary, it is widely distributed in the central and peripheral nervous systems. PACAP is important in the control of endocrine and homeostatic processes, such as secretion of pituitary and gut hormones and food intake. 
Pharmacological Action:   Growth Substances
Vasodilator Agents
Neurotransmitter Agents
 
History Note English:   2006(1990) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50569 
Unique Identifier:   D051219 

Occurrence in VHL:
 
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