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Descriptor English: Poloxamer
Descriptor Spanish: Poloxámero
Descriptor poloxámero
Entry term(s) Pluronic
poloxámeros
Scope note: Copolímero de bloque, no iónico, de polioxietileno-polioxipropileno, de fórmula general HO(C2H4O)a(-C3H6O)b(C2H4O)aH. Está disponible en diferentes grados, de líquidos a sólidos. Se utiliza como agente emulsionante, solubilizante, surfactante y humectante en antibióticos. El poloxámero también se utiliza en pomadas, como base de supositorios y como aglutinante y para el revestimiento de tabletas (Martindale The Extra Pharmacopoeia, 31st ed).
Descriptor Portuguese: Poloxâmero
Descriptor French: Poloxamère
Entry term(s): 188s, Poloxamer
213s, Poloxamer
2930s, Poloxamer
338s, Poloxamer
407s, Poloxamer
F68s, Pluronic
Pluronic
Pluronic F 108
Pluronic F 127
Pluronic F 68
Pluronic F-108
Pluronic F-127
Pluronic F-68
Pluronic F108
Pluronic F127
Pluronic F68
Pluronic F68s
Pluronic L 101
Pluronic L 121
Pluronic L 81
Pluronic L-101
Pluronic L-121
Pluronic L-81
Pluronic L101
Pluronic L121
Pluronic L81
Pluronics
Poloxalkol
Poloxalkols
Poloxamer 188
Poloxamer 188s
Poloxamer 213
Poloxamer 213s
Poloxamer 2930
Poloxamer 2930s
Poloxamer 338
Poloxamer 338s
Poloxamer 407
Poloxamer 407s
Poloxamers
Tree number(s): D02.033.455.250.700.682
D05.750.741.667
D25.720.741.667
J01.637.051.720.741.667
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020442
Scope note: A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AN analysis
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
Pharm Action: Excipients
Surface-Active Agents
Registry Number: 106392-12-5
CAS Type 1 Name: alpha-Hydro-omega-hydroxypoly(oxyethylene)a-poly(oxopropylene)b-poly(oxyethylene)a block copolymer
Previous Indexing: Poloxalene (1976-1998)
Public MeSH Note: 99; for POLOXAMERS see POLOXALENE 1974-98
History Note: 99; for POLOXAMERS use POLOXALENE 1974-98
DeCS ID: 33784
Unique ID: D020442
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1999/01/01
Date of Entry: 1998/06/10
Revision Date: 2020/05/27
Poloxamer - Preferred
Concept UI M0030100
Scope note A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)
Preferred term Poloxamer
Poloxamer 188 - Narrower
Concept UI M0030096
Preferred term Poloxamer 188
Entry term(s) 188s, Poloxamer
Poloxamer 188s
Poloxamer 338 - Narrower
Concept UI M0030093
Preferred term Poloxamer 338
Entry term(s) 338s, Poloxamer
Poloxamer 338s
Poloxamer 407 - Narrower
Concept UI M0030099
Preferred term Poloxamer 407
Entry term(s) 407s, Poloxamer
Poloxamer 407s
Poloxamers - Broader
Concept UI M0030095
Preferred term Poloxamers
Pluronic F-108 - Narrower
Concept UI M0030087
Preferred term Pluronic F-108
Entry term(s) Pluronic F 108
Pluronic F108
Pluronic F-127 - Narrower
Concept UI M0030088
Preferred term Pluronic F-127
Entry term(s) Pluronic F 127
Pluronic F127
Pluronic F68 - Narrower
Concept UI M0030089
Preferred term Pluronic F68
Entry term(s) F68s, Pluronic
Pluronic F 68
Pluronic F-68
Pluronic F68s
Pluronic L-101 - Narrower
Concept UI M0030090
Preferred term Pluronic L-101
Entry term(s) Pluronic L 101
Pluronic L101
Pluronic L-121 - Narrower
Concept UI M0030091
Preferred term Pluronic L-121
Entry term(s) Pluronic L 121
Pluronic L121
Pluronic L-81 - Narrower
Concept UI M0030092
Preferred term Pluronic L-81
Entry term(s) Pluronic L 81
Pluronic L81
Pluronics - Narrower
Concept UI M0030086
Preferred term Pluronics
Entry term(s) Pluronic
Poloxalkol - Narrower
Concept UI M0030094
Preferred term Poloxalkol
Entry term(s) Poloxalkols
Poloxamer 213 - Narrower
Concept UI M0030097
Preferred term Poloxamer 213
Entry term(s) 213s, Poloxamer
Poloxamer 213s
Poloxamer 2930 - Narrower
Concept UI M0030098
Preferred term Poloxamer 2930
Entry term(s) 2930s, Poloxamer
Poloxamer 2930s



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