Search on: POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B 
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Descriptor English:   Positive Transcriptional Elongation Factor B 
Descriptor Spanish:   Factor B de Elongación Transcripcional Positiva 
Descriptor Portuguese:   Fator B de Elongação Transcricional Positiva 
Synonyms English:   P-TEFb
Positive Transcription Elongation Factor B
tat Associated Kinase
tat-Associated Kinase  
Tree Number:   D08.811.913.696.620.682.700.626
D12.776.930.955.500
Definition English:   A transcriptional elongation factor complex that is comprised of a heterodimer of CYCLIN-DEPENDENT KINASE 9 and one of several CYCLINS including TYPE T CYCLINS and cyclin K. It functions by phosphorylating the carboxy-terminal domain of RNA POLYMERASE II. 
History Note English:   2004; use POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B (NM) 1996-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   38314 
Unique Identifier:   D042925 

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