Search on: PRALIDOXIME COMPOUNDS 
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Descriptor English:   Pralidoxime Compounds 
Descriptor Spanish:   Compuestos de Pralidoxima 
Descriptor Portuguese:   Compostos de Pralidoxima 
Synonyms English:   2 PAM Compounds
2-PAM Compounds
Compounds, 2-PAM
Compounds, Pralidoxime
Pyridine Aldoxime Methyl Compounds  
Tree Number:   D02.092.570.665.535
Definition English:   Various salts of a quaternary ammonium oxime that reconstitute inactivated acetylcholinesterase, especially at the neuromuscular junction, and may cause neuromuscular blockade. They are used as antidotes to organophosphorus poisoning as chlorides, iodides, methanesulfonates (mesylates), or other salts. 
History Note English:   65(63) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   11657 
Unique Identifier:   D011220 

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