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Descriptor English: Prekallikrein
Descriptor Spanish: Precalicreína
Descriptor precalicreína
Entry term(s) factor de Fletcher
procalicreína plasmática
Scope note: Proteína plasmática precursora de la calicreína. Se ha observado que el plasma que es deficiente en precalicreína es anormal en lo que se refiere a la formación de tromboplastina, la generación de cinina, la evolución de una globulina de permeabilidad y la formación de plasmina. La ausencia de precalicreína en el plasma causa una enfermedad congénita, la deficiencia del factor de Fletcher.
Descriptor Portuguese: Pré-Calicreína
Descriptor French: Prékallicréine
Entry term(s): Factor, Fletcher
Fletcher Factor
Kallikreinogen
Plasma Prokallikrein
Plasma Prokallikrein A
Prokallikrein A, Plasma
Prokallikrein, Plasma
Tree number(s): D08.622.658
D08.811.277.656.300.760.442.725
D08.811.277.656.959.350.442.725
D12.776.124.125.597.712
D12.776.811.243.658
D23.119.597.712
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011288
Scope note: A plasma protein which is the precursor of kallikrein. Plasma that is deficient in prekallikrein has been found to be abnormal in thromboplastin formation, kinin generation, evolution of a permeability globulin, and plasmin formation. The absence of prekallikrein in plasma leads to Fletcher factor deficiency, a congenital disease.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 9055-02-1
CAS Type 1 Name: Kallikreinogen
Previous Indexing: Blood Coagulation Factors (1973-1975)
Enzyme Precursors (1973-1975)
Kallikrein (1973-1975)
Public MeSH Note: 89; was see under KALLIKREIN 1976-88
History Note: 89(76); was see under KALLIKREINS 1976-88
Related: Coagulants MeSH
DeCS ID: 22264
Unique ID: D011288
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1975/07/25
Revision Date: 2009/07/06
Prekallikrein - Preferred
Concept UI M0017530
Scope note A plasma protein which is the precursor of kallikrein. Plasma that is deficient in prekallikrein has been found to be abnormal in thromboplastin formation, kinin generation, evolution of a permeability globulin, and plasmin formation. The absence of prekallikrein in plasma leads to Fletcher factor deficiency, a congenital disease.
Preferred term Prekallikrein
Entry term(s) Factor, Fletcher
Fletcher Factor
Kallikreinogen
Plasma Prokallikrein
Prokallikrein, Plasma
Plasma Prokallikrein A - Narrower
Concept UI M0017529
Preferred term Plasma Prokallikrein A
Entry term(s) Prokallikrein A, Plasma



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