Search on: PROGRAMMED CELL DEATH 1 RECEPTOR 
Descriptors Found: 1
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Descriptor English:   Programmed Cell Death 1 Receptor 
Descriptor Spanish:   Receptor de Muerte Celular Programada 1 
Descriptor Portuguese:   Receptor de Morte Celular Programada 1 
Synonyms English:   Antigen, CD279
Antigens, CD279
CD279 Antigen
CD279 Antigens
PD 1 Receptor
PD-1 Receptor
PD1 Receptor
Programmed Cell Death 1 Protein
Receptor, PD-1
Receptor, PD1  
Tree Number:   D12.776.543.750.705.222.875
D23.050.301.264.894.790
D23.101.100.894.790
Definition English:   An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE. 
See Related English:   Immunoglobulin Domains
 
History Note English:   2012 
Allowable Qualifiers English:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Record Number:   54636 
Unique Identifier:   D061026 

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