Search on: PROTO-ONCOGENE PROTEINS C-BCL-2 
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Descriptor English:   Proto-Oncogene Proteins c-bcl-2 
Descriptor Spanish:   Proteínas Proto-Oncogénicas c-bcl-2 
Descriptor Portuguese:   Proteínas Proto-Oncogênicas c-bcl-2 
Synonyms English:   B Cell Leukemia 2 Family Proteins
B-Cell Leukemia 2 Family Proteins
BCL2 Family Proteins
BCL2 Proteins
Family Proteins, BCL2
Proteins, BCL2
Proteins, BCL2 Family
Proto Oncogene Proteins c bcl 2
Proto-Oncogene Proteins, bcl-2
bcl 2 Proto Oncogene Proteins
bcl-2 Proto-Oncogene Proteins
c bcl 2 Proteins
c-bcl-2 Proteins
c-bcl-2, Proto-Oncogene Proteins  
Tree Number:   D12.644.360.075.718
D12.776.476.075.718
D12.776.624.664.700.169
Definition English:   Membrane proteins encoded by the BCL-2 GENES and serving as potent inhibitors of cell death by APOPTOSIS. The proteins are found on mitochondrial, microsomal, and NUCLEAR MEMBRANE sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma. 
History Note English:   97; was PROTO-ONCOGENE PROTEIN BCL-2 (NM) 1989-96 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   33061 
Unique Identifier:   D019253 

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