Descriptors Found: 1
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Descriptor English:   Receptors, Cytoplasmic and Nuclear 
Descriptor Spanish:   Receptores Citoplasmáticos y Nucleares 
Descriptor Portuguese:   Receptores Citoplasmáticos e Nucleares 
Synonyms English:   Cytoplasmic Hormone Receptors
Cytoplasmic Receptors
Cytoplasmic and Nuclear Receptors
Cytosol and Nuclear Receptors
Cytosolic and Nuclear Receptors
Hormone Receptors, Cytoplasmic
Hormone Receptors, Nuclear
Intracellular Membrane Receptors
Membrane Receptors, Intracellular
Nuclear Hormone Receptors
Nuclear Receptors
Nuclear and Cytoplasmic Receptors
Receptors, Cytoplasmic
Receptors, Cytoplasmic Hormone
Receptors, Cytosol and Nuclear
Receptors, Cytosolic and Nuclear
Receptors, Intracellular Membrane
Receptors, Nuclear
Receptors, Nuclear Hormone
Receptors, Nuclear and Cytoplasmic  
Tree Number:   D12.776.826
Definition English:   Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS. 
Indexing Annotation English:   general or unspecified; prefer specifics; for hormone receptors, see note at RECEPTORS, CELL SURFACE
History Note English:   94 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   31129 
Unique Identifier:   D018160 

Occurrence in VHL: