Search on: RECEPTORS, GLUTAMATE 
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Descriptor English:   Receptors, Glutamate 
Descriptor Spanish:   Receptores de Glutamato 
Descriptor Portuguese:   Receptores de Glutamato 
Synonyms English:   Excitatory Amino Acid Receptor
Excitatory Amino Acid Receptors
Glutamate Receptor
Glutamate Receptors
Receptor, Glutamate
Receptors, Excitatory Amino Acid  
Tree Number:   D12.776.543.750.720.200.450
Definition English:   Cell-surface proteins that bind glutamate and trigger changes which influence the behavior of cells. Glutamate receptors include ionotropic receptors (AMPA, kainate, and N-methyl-D-aspartate receptors), which directly control ion channels, and metabotropic receptors which act through second messenger systems. Glutamate receptors are the most common mediators of fast excitatory synaptic transmission in the central nervous system. They have also been implicated in the mechanisms of memory and of many diseases. 
Indexing Annotation English:   general or unspecified; prefer specifics
Entry Combination - descr/qualif English:   Receptors, Glutamate/antagonists & inhibitors use Excitatory Amino Acid Antagonists
Receptors, Glutamate/agonists use Excitatory Amino Acid Agonists
 
History Note English:   93; was GLUTAMATE RECEPTOR (NM) 1980-92; EXCITATORY AMINO ACID RECEPTORS & RECEPTORS, EXCITATORY AMINO ACID were see RECEPTORS, AMINO ACID 1993 
Allowable Qualifiers English:  
AD administration & dosage AN analysis
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Record Number:   30561 
Unique Identifier:   D017470 

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