Descriptors Found: 1
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 1 / 1 DeCS     
Descriptor English:   Receptors, Tumor Necrosis Factor, Member 14 
Descriptor Spanish:   Miembro 14 de Receptores del Factor de Necrosis Tumoral 
Descriptor Portuguese:   Membro 14 de Receptores do Fator de Necrose Tumoral 
Synonyms English:   Entry Mediator, Herpesvirus
HVEM Protein
Herpesvirus Entry Mediator
HveA Protein
Tumor Necrosis Factor Receptor Subfamily, Member 14
Tumor Necrosis Factor Receptor Superfamily, Member 14  
Tree Number:   D12.776.543.750.705.852.760.500
Definition English:   A novel member of the tumor-necrosis factor receptor family that can also mediate HERPES SIMPLEX VIRUS TYPE 1 entry into cells. It has specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 and the homotrimeric form of LYMPHOTOXIN-ALPHA. The receptor is abundantly expressed on T-LYMPHOCYTES and may play a role in regulating lymphocyte activation. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS. 
History Note English:   2007(1997) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52393 
Unique Identifier:   D053240 

Occurrence in VHL: