Descriptors Found: 1
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Descriptor English:   Ribosome Inactivating Proteins 
Descriptor Spanish:   Proteínas Inactivadoras de Ribosomas 
Descriptor Portuguese:   Proteínas Inativadoras de Ribossomos 
Synonyms English:   Adenosine Glycosidase, Polynucleotide
Glycosidase, Polynucleotide Adenosine
Glycosylase, RNA
Inactivating Proteins, Ribosome
N-Glycosidase, RNA
N-Glycosylases, rRNA
Polynucleotide Adenosine Glycosidase
Proteins, Ribosome Inactivating
RIP (Ribosome Inactivating Proteins)
RNA Glycosylase
RNA N Glycosidase
RNA N-Glycosidase
rRNA N Glycosylases
rRNA N-Glycosylases  
Tree Number:   D08.811.277.450.430.700
Definition English:   N-Glycosidases that remove adenines from RIBOSOMAL RNA, depurinating the conserved alpha-sarcin loop of 28S RIBOSOMAL RNA. They often consist of a toxic A subunit and a binding lectin B subunit. They may be considered as PROTEIN SYNTHESIS INHIBITORS. They are found in many PLANTS and have cytotoxic and antiviral activity. 
Pharmacological Action:   Protein Synthesis Inhibitors
History Note English:   2008(1988) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52713 
Unique Identifier:   D054788 

Occurrence in VHL: