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Descriptor English: Serotonin
Descriptor Spanish: Serotonina
Descriptor serotonina
Entry term(s) 5-HT
5-hidroxitriptamina
Scope note: Mensajero y regulador bioquímico, sintetizado a partir del aminoácido esencial L-TRIPTÓFANO. En los humanos se encuentra principalmente en el sistema nervioso central, el tubo digestivo y las plaquetas. La serotonina interviene en diversas funciones fisiológicas importantes icomo la neurotransmisión, la movilidad gastrointestinal, la hemostasia y la integridad cardiovascular. Las múltiples familias de receptores (RECEPTORES DE SEROTONINA) explican su amplio espectro de acciones fisiológicas y la distribución de este mediador bioquímico.
Descriptor Portuguese: Serotonina
Descriptor French: Sérotonine
Entry term(s): 3-(2-Aminoethyl)-1H-indol-5-ol
5 Hydroxytryptamine
5-HT
5-Hydroxytryptamine
Enteramine
Hippophaine
Hydroxytryptamine
Tree number(s): D02.092.211.215.801.852
D03.633.100.473.914.814
D23.469.050.650
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012701
Scope note: A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
Annotation: /antag = SEROTONIN ANTAGONISTS but consider also SELECTIVE SEROTONIN REUPTAKE INHIBITORS
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Entry Combination: antagonists & inhibitors:Serotonin Antagonists
agonists:Serotonin Receptor Agonists
Pharm Action: Serotonin Receptor Agonists
Registry Number: 333DO1RDJY
CAS Type 1 Name: 1H-Indol-5-ol, 3-(2-aminoethyl)-
Public MeSH Note: HYDROXYTRYPTAMINE was see SEROTONIN 1975-92
Online Note: use SEROTONIN to search HYDROXYTRYPTAMINE 1975-92
History Note: HYDROXYTRYPTAMINE was see SEROTONIN 1975-92
Related: Receptors, Serotonin MeSH
Serotonin Agents MeSH
Serotonin Syndrome MeSH
DeCS ID: 24311
Unique ID: D012701
NLM Classification: QV 126
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1960/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Serotonin - Preferred
Concept UI M0019683
Scope note A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
Preferred term Serotonin
Entry term(s) 3-(2-Aminoethyl)-1H-indol-5-ol
5 Hydroxytryptamine
5-HT
5-Hydroxytryptamine
Enteramine
Hippophaine
Hydroxytryptamine - Related but not broader or narrower
Concept UI M0019684
Preferred term Hydroxytryptamine



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