Search on: SILYMARIN 
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Descriptor English:   Silymarin 
Descriptor Spanish:   Silimarina 
Descriptor Portuguese:   Silimarina 
Synonyms English:   Carsil
Tree Number:   D03.383.663.283.266.450.268.777
Definition English:   A mixture of flavonoids extracted from seeds of the MILK THISTLE, Silybum marianum. It consists primarily of silybin and its isomers, silicristin and silidianin. Silymarin displays antioxidant and membrane stabilizing activity. It protects various tissues and organs against chemical injury, and shows potential as an antihepatoxic agent. 
Pharmacological Action:   Antioxidants
Protective Agents
See Related English:   Milk Thistle
History Note English:   91(75); was see under FLAVONES 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   13218 
Unique Identifier:   D012838 

Occurrence in VHL: