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Descriptor English: Sparsomycin
Descriptor Spanish: Esparsomicina
Descriptor esparsomicina
Scope note: Antibiótico antitumoral producido por el Streptomyces sparsogenes. Inhibe la síntesis proteica en los sistemas ribosómicos 70S y 80S.
Descriptor Portuguese: Esparsomicina
Descriptor French: Sparsomycine
Tree number(s): D03.383.742.698.715
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013033
Scope note: An antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems.
Annotation: an antineoplastic antibiotic
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antibiotics, Antineoplastic
Protein Synthesis Inhibitors
Registry Number: 6C940P63E7
CAS Type 1 Name: 2-Propenamide, N-(1-(hydroxymethyl)-2-(((methylthio)methyl)sulfinyl)ethyl)-3-(1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-5-pyrimidinyl)-, (R-(R*,S*-(E)))-
Previous Indexing: Antibiotics (1974)
Antibiotics, Antineoplastic (1974)
Ribonucleosides (1974)
Public MeSH Note: 91; was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90
History Note: 91(75); was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90
DeCS ID: 13414
Unique ID: D013033
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/05/31
Sparsomycin - Preferred
Concept UI M0020197
Scope note An antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems.
Preferred term Sparsomycin



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