Search on: SPHINGOLIPIDS 
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Descriptor English:   Sphingolipids 
Descriptor Spanish:   Esfingolípidos 
Descriptor Portuguese:   Esfingolipídeos 
Synonyms English:   Lysosphingolipids  
Tree Number:   D10.570.877
Definition English:   A class of membrane lipids that have a polar head and two nonpolar tails. They are composed of one molecule of the long-chain amino alcohol sphingosine (4-sphingenine) or one of its derivatives, one molecule of a long-chain acid, a polar head alcohol and sometimes phosphoric acid in diester linkage at the polar head group. (Lehninger et al, Principles of Biochemistry, 2nd ed) 
See Related English:   Sphingosine
 
History Note English:   72(71); was see under LIPIDS 1963-71 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   13490 
Unique Identifier:   D013107 

Occurrence in VHL:
 
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MEDLINE    
BBO    
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