Search on: SULINDAC 
Descriptors Found: 1
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Descriptor English:   Sulindac 
Descriptor Spanish:   Sulindac 
Descriptor Portuguese:   Sulindaco 
Synonyms English:   Aclin
Apo Sulin
Apo-Sulin
Arthrobid
Arthrocine
Chibret
Clinoril
Copal
Kenalin
Klinoril
MK 231
MK-231
MK231
Novo Sundac
Novo-Sundac
Nu Sulindac
Nu-Sulindac
Sulindal  
Tree Number:   D02.455.426.559.847.486.875
D04.615.486.875
Definition English:   A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects. 
Pharmacological Action:   Anti-Inflammatory Agents, Non-Steroidal
Antineoplastic Agents
Cyclooxygenase Inhibitors
 
History Note English:   90(79); was see under INDENES 1979-89 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   27862 
Unique Identifier:   D013467 

Occurrence in VHL:
 
LILACS    
MEDLINE    
BBO    
IBECS    

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