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Descriptor English:   Talin 
Descriptor Spanish:   Talina 
Descriptor Portuguese:   Talina 
Synonyms English:   Band 2 Protein
Platelet Protein p235
Protein p235, Platelet
Protein, Band 2  
Tree Number:   D12.776.220.985
Definition English:   A 235-kDa cytoplasmic protein that is also found in platelets. It has been localized to regions of cell-substrate adhesion. It binds to INTEGRINS; VINCULIN; and ACTINS and appears to participate in generating a transmembrane connection between the extracellular matrix and the cytoskeleton. 
Indexing Annotation English:   a cytoplasmic protein; /drug eff /ultrastruct permitted
History Note English:   92; was TALIN (NM) 1984-91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   29792 
Unique Identifier:   D016608 

Occurrence in VHL:
 
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