| Descriptor English: | Teprotide | ||||
| Descriptor Spanish: |
Teprotido
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| Descriptor Portuguese: | Teprotida | ||||
| Descriptor French: | Téprotide | ||||
| Entry term(s): |
BPP-9a Bradykinin Potentiating Peptide 9a Bradykinin-Potentiating Peptide 9a Enzyme Inhibitor, Nonapeptide-Converting Nonapeptide Converting Enzyme Inhibitor Nonapeptide-Converting Enzyme Inhibitor Peptide 9a, Bradykinin-Potentiating SQ-20881 |
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| Tree number(s): |
D12.644.456.810 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D013722 | ||||
| Scope note: | A synthetic nonapeptide (Pyr-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro) which is identical to the peptide from the venom of the snake, Bothrops jararaca. It inhibits kininase II and ANGIOTENSIN I and has been proposed as an antihypertensive agent. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Pharm Action: |
Angiotensin-Converting Enzyme Inhibitors Antihypertensive Agents |
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| Registry Number: | C3E5QBF1R6 | ||||
| CAS Type 1 Name: | Bradykinin potentiator B, 2-L-tryptophan-3-de-L-leucine-4-de-L-proline-8-L-glutamine- | ||||
| Previous Indexing: |
Oligopeptides (1973-1974) Peptides (1966-1972) Snakes (1966-1972) |
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| Public MeSH Note: | 91; was see under OLIGOPEPTIDES 1981-90, was SQ 20881 see under OLIGOPEPTIDES 1975-80; SQ 20881 was see TEPROTIDE 1981-93; NONAPEPTIDE CONVERTING-ENZYME INHIBITOR was indexed under OLIGOPEPTIDES 1975-93 |
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| Online Note: | use TEPROTIDE to search SQ 20881 1975-93; use TEPROTIDE (NM) to search NONAPEPTIDE CONVERTING-ENZYME INHIBITOR 1980-93 |
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| History Note: | 91(81); was see under OLIGOPEPTIDES 1981-90, was SQ 20881 see under OLIGOPEPTIDES 1975-80; SQ 20881 was see TEPROTIDE 1981-93; NONAPEPTIDE CONVERTING-ENZYME INHIBITOR was (NM) 1975-93 |
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| DeCS ID: | 23477 | ||||
| Unique ID: | D013722 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 1991/01/01 | ||||
| Date of Entry: | 1974/11/19 | ||||
| Revision Date: | 2013/07/08 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Teprotide
- Preferred
SQ-20881
- Narrower
| Concept UI |
M0021171 |
| Scope note | A synthetic nonapeptide (Pyr-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro) which is identical to the peptide from the venom of the snake, Bothrops jararaca. It inhibits kininase II and ANGIOTENSIN I and has been proposed as an antihypertensive agent. |
| Preferred term | Teprotide |
| Entry term(s) |
BPP-9a Bradykinin Potentiating Peptide 9a Bradykinin-Potentiating Peptide 9a Enzyme Inhibitor, Nonapeptide-Converting Nonapeptide Converting Enzyme Inhibitor Nonapeptide-Converting Enzyme Inhibitor Peptide 9a, Bradykinin-Potentiating |
| Concept UI |
M0373891 |
| Preferred term | SQ-20881 |
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