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Descriptor English: Thrombopoietin
Descriptor Spanish: Trombopoyetina
Descriptor trombopoyetina
Entry term(s) factor de crecimiento y de desarrollo de megacariocitos
ligando c-mpl
Scope note: Factor humoral que estimula la producción de trombocitos (PLAQUETAS). La trombopoyetina estimula la proliferación de los MEGACARIOCITOS de la médula ósea y la liberación de las plaquetas. El proceso recibe la denominación de TROMBOPOYESIS.
Descriptor Portuguese: Trombopoetina
Descriptor French: Thrombopoïétine
Entry term(s): Ligand, c-mpl
Ligand, mpl
MGDF Factor
Megakaryocyte Colony Stimulating Factor
Megakaryocyte Growth and Development Factor
Myeloproliferative Leukemia Virus Oncogene Ligand
Thrombocytopoiesis Stimulating Factor
Thrombocytopoiesis-Stimulating Factor
Thrombocytopoietin
c-mpl Ligand
mpl Ligand
Tree number(s): D12.644.276.374.410.240.750
D12.776.395.240.750
D12.776.467.374.410.240.750
D23.529.374.410.240.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013926
Scope note: A humoral factor that stimulates the production of thrombocytes (BLOOD PLATELETS). Thrombopoietin stimulates the proliferation of bone marrow MEGAKARYOCYTES and their release of blood platelets. The process is called THROMBOPOIESIS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 9014-42-0
CAS Type 1 Name: Thrombopoietin
Public MeSH Note: 91; was see under GLYCOPROTEINS 1976-90; was see under BLOOD PLATELETS 1975
History Note: 91(66); was see under GLYCOPROTEINS 1976-90; was see under BLOOD PLATELETS 1975
DeCS ID: 14311
Unique ID: D013926
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2015/06/23
Thrombopoietin - Preferred
Concept UI M0021434
Scope note A humoral factor that stimulates the production of thrombocytes (BLOOD PLATELETS). Thrombopoietin stimulates the proliferation of bone marrow MEGAKARYOCYTES and their release of blood platelets. The process is called THROMBOPOIESIS.
Preferred term Thrombopoietin
Entry term(s) Ligand, c-mpl
Ligand, mpl
MGDF Factor
Megakaryocyte Colony Stimulating Factor
Megakaryocyte Growth and Development Factor
Myeloproliferative Leukemia Virus Oncogene Ligand
Thrombocytopoiesis Stimulating Factor
Thrombocytopoiesis-Stimulating Factor
Thrombocytopoietin
c-mpl Ligand
mpl Ligand



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