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Descriptor English: Toremifene
Descriptor Spanish: Toremifeno
Descriptor toremifeno
Scope note: Modulador selectivo del receptor de estrógeno (MSRE) de primera generación. Al igual que el TAMOXIFENO, es un agonista de los estrógenos en el tejido óseo y en el metabolismo del colesterol, pero es un antagonista en los tejidos mamario y uterino.
Descriptor Portuguese: Toremifeno
Descriptor French: Torémifène
Entry term(s): Citrate, Toremifene
FC 1157a
FC-1157a
FC1157a
Fareston
Toremifene Citrate
Toremifene Citrate (1:1)
Toremifene, (E)-Isomer
Tree number(s): D02.455.426.559.389.150.700.900.900
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017312
Scope note: A first generation selective estrogen receptor modulator (SERM). Like TAMOXIFEN, it is an estrogen agonist for bone tissue and cholesterol metabolism but is antagonistic on mammary and uterine tissue.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents, Hormonal
Selective Estrogen Receptor Modulators
Bone Density Conservation Agents
Registry Number: 7NFE54O27T
CAS Type 1 Name: Ethanamine, 2-(4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (Z)-
Previous Indexing: Tamoxifen/analogs & derivatives (1985-1992)
Public MeSH Note: 93; TOREMIFENE was indexed under TAMOXIFEN/analogs & derivatives 1985-92
Online Note: use TOREMIFENE (NM) to search TOREMIFENE 1985-92
History Note: 93; was TOREMIFENE (NM) 1985-92
DeCS ID: 30475
Unique ID: D017312
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/05/20
Revision Date: 2013/07/08
Toremifene - Preferred
Concept UI M0026287
Scope note A first generation selective estrogen receptor modulator (SERM). Like TAMOXIFEN, it is an estrogen agonist for bone tissue and cholesterol metabolism but is antagonistic on mammary and uterine tissue.
Preferred term Toremifene
Toremifene, (E)-Isomer - Related but not broader or narrower
Concept UI M0329298
Preferred term Toremifene, (E)-Isomer
Toremifene Citrate - Narrower
Concept UI M0026288
Preferred term Toremifene Citrate
Entry term(s) Citrate, Toremifene
Toremifene Citrate (1:1)
Fareston - Narrower
Concept UI M0026289
Preferred term Fareston
FC-1157a - Narrower
Concept UI M0026290
Preferred term FC-1157a
Entry term(s) FC 1157a
FC1157a



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