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Descriptor English: Trifluridine
Descriptor Spanish: Trifluridina
Descriptor trifluridina
Entry term(s) trifluorotimidina
Scope note: Derivado antiviral de la TIMIDINA, utilizado principalmente en el tratamiento de la queratoconjuntivitis primaria y de la queratitis epitelial recurrente producida por el virus del herpes simple.
Descriptor Portuguese: Trifluridina
Descriptor French: Trifluorothymidine
Entry term(s): 2'-deoxy-5-(trifluoromethyl)uridine
5 Trifluoromethyl 2' deoxyuridine
5-Trifluoromethyl-2'-deoxyuridine
TFT Ophtiole
Triflumann
Trifluoridine
Trifluorothymidine
Viromidin
Virophta
Viroptic
Tree number(s): D03.383.742.680.705.900
D13.570.230.855.900
D13.570.685.705.900
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D014271
Scope note: An antiviral derivative of THYMIDINE used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HERPES SIMPLEX virus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p557)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimetabolites
Antiviral Agents
Registry Number: RMW9V5RW38
CAS Type 1 Name: Thymidine, alpha,alpha,alpha-trifluoro-
Previous Indexing: Fluorine (1972-1974)
Thymidine (1972-1974)
Public MeSH Note: 1974; see TRIFLUOROTHYMIDINE 1975-1991, see THYMIDINE 1975-1990, 2'-DEOXY-5-(TRIFLUOROMETHYL)URIDINE was indexed under DEOXYURIDINE
History Note: 1974(1992)
DeCS ID: 30424
Unique ID: D014271
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2017/05/24
Trifluridine - Preferred
Concept UI M0021960
Scope note An antiviral derivative of THYMIDINE used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HERPES SIMPLEX virus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p557)
Preferred term Trifluridine
Entry term(s) 2'-deoxy-5-(trifluoromethyl)uridine
5 Trifluoromethyl 2' deoxyuridine
5-Trifluoromethyl-2'-deoxyuridine
Trifluoridine
Trifluorothymidine
Triflumann - Narrower
Concept UI M0476898
Preferred term Triflumann
Virophta - Narrower
Concept UI M0476900
Preferred term Virophta
Viroptic - Narrower
Concept UI M0373255
Preferred term Viroptic
TFT Ophtiole - Narrower
Concept UI M0476897
Preferred term TFT Ophtiole
Viromidin - Narrower
Concept UI M0476899
Preferred term Viromidin



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