Search on: X-LINKED INHIBITOR OF APOPTOSIS PROTEIN 
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Descriptor English:   X-Linked Inhibitor of Apoptosis Protein 
Descriptor Spanish:   Proteína Inhibidora de la Apoptosis Ligada a X 
Descriptor Portuguese:   Proteínas Inibidoras de Apoptose Ligadas ao Cromossomo X 
Synonyms English:   IAP Protein, X-Linked
X Linked IAP Protein
X Linked Inhibitor of Apoptosis Protein
X-Linked IAP Protein
XIAP Protein  
Tree Number:   D08.811.464.938.750.210.750
D12.644.360.075.437.750
D12.776.476.075.437.750
Definition English:   An inhibitor of apoptosis protein that is translated by a rare cap-independent mechanism. It blocks caspase-mediated cellular destruction by inhibiting CASPASE 3; CASPASE 7; and CASPASE 9. 
Pharmacological Action:   Caspase Inhibitors
 
History Note English:   2006(1996) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50804 
Unique Identifier:   D051636 

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