Pesquisa sobre: CISPLATIN 
Descritores Encontrados: 1
Mostrando: 1 .. 1  

 1 / 1 DeCS     
Descritor Inglês:   Cisplatin 
Descritor Espanhol:   Cisplatino 
Descritor Português:   Cisplatino 
Sinônimos Inglês:   Biocisplatinum
Diamminodichloride, Platinum
Dichlorodiammineplatinum
NSC-119875
Platidiam
Platino
Platinol
Platinum Diamminodichloride
cis Diamminedichloroplatinum
cis Platinum
cis-Diamminedichloroplatinum
cis-Diamminedichloroplatinum(II)
cis-Dichlorodiammineplatinum(II)
cis-Platinum  
Categoria:   D01.210.375
D01.625.125
D01.710.100
Definição Inglês:   An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle. 
Ação Farmacológica:   Antineoplastic Agents
Cross-Linking Reagents
Radiation-Sensitizing Agents
 
Nota Histórica Inglês:   84(81); was see under DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1981-83; was PLATINUM DIAMMINODICHLORIDE see under DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1974-80; DIAMMONIUM CHLOROPLATINUM COMPOUNDS was heading 1974-83 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Número do Registro:   2971 
Identificador Único:   D002945 

Ocorrência na BVS:
 
LILACS    
MEDLINE    
BDENF    
HomeoIndex    
IBECS    

Similar:

 
DeCS