Search
Descriptor English: Clarithromycin
Descriptor Spanish: Claritromicina
Descriptor claritromicina
Scope note: Antibiótico macrólido semisintético derivado de la ERITROMICINA, activo frente diversos microorganismos. Inhibe la SÍNTESIS PROTEICA en las BACTERIAS al unirse reversiblemente a las subunidades ribosómicas 50S. Así se inhibe la translocación del aminoacil ARN de transferencia y se previene la elongación de la cadena peptídica.
Descriptor Portuguese: Claritromicina
Descriptor French: Clarithromycine
Entry term(s): 6-O-Methylerythromycin
A 56268
A-56268
A56268
Biaxin
TE 031
TE-031
TE031
Tree number(s): D02.540.576.500.992.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017291
Scope note: A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Protein Synthesis Inhibitors
Cytochrome P-450 CYP3A Inhibitors
Registry Number: H1250JIK0A
CAS Type 1 Name: Erythromycin, 6-O-methyl-
Previous Indexing: Erythromycin/analogs & derivatives (1987-1992)
Public MeSH Note: 93; CLARITHROMYCIN was indexed under ERYTHROMYCIN/analogs & derivatives 1987-92
Online Note: use CLARITHROMYCIN (NM) to search CLARITHROMYCIN 1987-92
History Note: 93; was CLARITHROMYCIN (NM) 1987-92
DeCS ID: 30785
Unique ID: D017291
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/05/07
Revision Date: 2015/06/22
Clarithromycin - Preferred
Concept UI M0026249
Scope note A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.
Preferred term Clarithromycin
Entry term(s) 6-O-Methylerythromycin
TE-031 - Narrower
Concept UI M0352014
Preferred term TE-031
Entry term(s) TE 031
TE031
A-56268 - Narrower
Concept UI M0352016
Preferred term A-56268
Entry term(s) A 56268
A56268
Biaxin - Narrower
Concept UI M0352015
Preferred term Biaxin



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey