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Descriptor English: Colistin
Descriptor Spanish: Colistina
Descriptor colistina
Entry term(s) polimixina E
Scope note: Antibiótico polipéptido cíclico obtenido de Bacillus colistinus. Está constituido por polimixinas E1 y E2 (o colistinas A, B y C), que actúan como detergentes en las membranas celulares. La colistina es menos tóxica que la polimixina B, pero por lo demás es similar; el metanosulfonato se administra por vía oral.
Descriptor Portuguese: Colistina
Descriptor French: Colistine
Entry term(s): Colimycin
Colisticin
Colistin Sulfate
Coly-Mycin
Polymyxin E
Sulfate, Colistin
Totazina
Tree number(s): D04.345.566.780.110
D10.477.750.110
D12.644.050.600.110
D12.644.066.500.600.110
D12.644.641.780.110
D12.776.543.695.054.600.110
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003091
Scope note: Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Registry Number: Z67X93HJG1
CAS Type 1 Name: Colistin
DeCS ID: 3122
Unique ID: D003091
NLM Classification: QV 350
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Colistin - Preferred
Concept UI M0004767
Scope note Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Preferred term Colistin
Entry term(s) Colimycin
Colisticin
Polymyxin E
Coly-Mycin - Narrower
Concept UI M0372333
Preferred term Coly-Mycin
Totazina - Narrower
Concept UI M0372332
Preferred term Totazina
Colistin Sulfate - Narrower
Concept UI M0004768
Preferred term Colistin Sulfate
Entry term(s) Sulfate, Colistin



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