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Descriptor English: Degenerin Sodium Channels
Descriptor Spanish: Canales de Sodio Degenerina
Descriptor canales del sodio degenerinas
Entry term(s) canales iónicos degenerina
degenerina
degenerinas
Scope note: Familia de canales del sodio mecanosensibles, existentes sobre todo en NEMATODOS, donde intervienen en la MECANOTRANSDUCCIÓN CELULAR. Los canales degenerinas están estructuralmente relacionados con los CANALES DEL SODIO EPITELIALES y reciben esta denominación porque la pérdida de su actividad se traduce en una degeneración celular.
Descriptor Portuguese: Canais de Sódio Degenerina
Descriptor French: Canaux sodiques de la famille des dégénérines
Entry term(s): Degenerin
Degenerin Ion Channels
Degenerin Sodium Ion Channels
Degenerins
Ion Channels, Degenerin
Sodium Channels, Degenerin
Tree number(s): D12.776.157.530.400.875.100
D12.776.543.550.450.875.100
D12.776.543.585.400.875.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D062626
Scope note: A family of mechanosensitive sodium channels found primarily in NEMATODES where they play a role in CELLULAR MECHANOTRANSDUCTION. Degenerin sodium channels are structurally-related to EPITHELIAL SODIUM CHANNELS and are named after the fact that loss of their activity results in cellular degeneration.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Sodium Channel Blockers
agonists:Sodium Channel Agonists
Previous Indexing: Epithelial Sodium Channels (2007-2012)
Ion Channels (1996-2006)
Nerve Tissue Proteins (2007-2012)
Public MeSH Note: 2013; DEGENERIN EPITHELIAL SODIUM CHANNELS (now DEGENERIN ION CHANNELS) was indexed under NERVE TISSUE PROTEINS and EPITHELIAL SODIUM CHANNEL 2007-2012, and under ION CHANNELS 1996-2006
History Note: 2013
DeCS ID: 54945
Unique ID: D062626
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2013/01/01
Date of Entry: 2012/07/03
Revision Date: 2016/07/01
Degenerin Sodium Channels - Preferred
Concept UI M0568826
Scope note A family of mechanosensitive sodium channels found primarily in NEMATODES where they play a role in CELLULAR MECHANOTRANSDUCTION. Degenerin sodium channels are structurally-related to EPITHELIAL SODIUM CHANNELS and are named after the fact that loss of their activity results in cellular degeneration.
Preferred term Degenerin Sodium Channels
Entry term(s) Degenerin
Degenerin Ion Channels
Degenerin Sodium Ion Channels
Degenerins
Ion Channels, Degenerin
Sodium Channels, Degenerin



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