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Descriptor English: Demecolcine
Descriptor Spanish: Demecolcina
Descriptor demecolcina
Scope note: Alcaloide aislado del Colchicum autumnale L. y utilizado como antineoplásico.
Descriptor Portuguese: Demecolcina
Descriptor French: Démécolcine
Entry term(s): Colcemid
Colcemide
Colchamine
Demecolcine, (+-)-Isomer
Tree number(s): D03.132.225.374
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003703
Scope note: An alkaloid isolated from Colchicum autumnale L. and used as an antineoplastic.
Annotation: /biosyn permitted if by plant
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents, Phytogenic
Tubulin Modulators
Registry Number: Z01IVE25KI
CAS Type 1 Name: Benzo(a)heptalen-9(5H)-one, 6,7-dihydro-1,2,3,10-tetramethoxy-7-(methylamino)-, (S)-
Previous Indexing: Alkaloids (1966-1971)
Antineoplastic Agents (1966-1971)
Colchicine (1966-1971)
Public MeSH Note: 73
History Note: 73(72)
DeCS ID: 3716
Unique ID: D003703
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Demecolcine - Preferred
Concept UI M0005796
Scope note An alkaloid isolated from Colchicum autumnale L. and used as an antineoplastic.
Preferred term Demecolcine
Entry term(s) Colchamine
Demecolcine, (+-)-Isomer - Narrower
Concept UI M0330549
Preferred term Demecolcine, (+-)-Isomer
Colcemide - Narrower
Concept UI M0352765
Preferred term Colcemide
Entry term(s) Colcemid



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