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Descriptor English: Enprostil
Descriptor Spanish: Enprostilo
Descriptor enprostilo
Scope note: Análñogo sintético de la PGE2 que tiene efecto inhibidor de la secreción de ácido gástrico, un efecto mucoprotector y un efecto postprandial de disminución de la gastrina. Se ha demostrado que es eficiente en el tratamiento de las úlceras gastroduodenales.
Descriptor Portuguese: Emprostila
Descriptor French: Enprostil
Entry term(s): Enprostil, (1R-(1(R*),2beta(1E,3R*),3alpha))-Isomer
Enprostil, (1R-(1alpha(S*),2beta(1E,3R*),3alpha))-Isomer
Enprostil, (1R-(1alpha,2beta(1E,3R*),3alpha))-Isomer
Enprostil, (1S-(1alpha(R*),2beta(1E,3R*),3alpha))-Isomer
Enprostil, (1S-(1alpha(S*),2beta(1E,3R*),3alpha))-Isomer
Enprostil, (1alpha(R*),2beta(1E,3R*),3alpha)-(+-)-Isomer
Enprostil, (1alpha(R*),2beta(1E,3S*),3alpha)-(+-)-Isomer
Enprostil, (1alpha,2alpha(1E,3S*),3beta)-(+-)-Isomer
Enprostil, (1alpha,2beta(1E,3R*),3alpha)-(+-)-Isomer
Gardrin
RS 84135
RS-84135
RS84135
Tree number(s): D10.251.355.255.550.775.450.350
D23.469.050.175.725.775.450.350
D23.469.700.660.250
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016620
Scope note: A synthetic PGE2 analog that has an inhibitory effect on gastric acid secretion, a mucoprotective effect, and a postprandial lowering effect on gastrin. It has been shown to be efficient and safe in the treatment of gastroduodenal ulcers.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Ulcer Agents
Registry Number: J4IP5Z9DAU
CAS Type 1 Name: 4,5-Heptadienoic acid, 7-(3-hydroxy-2-(3-hydroxy-4-phenoxy-1-butenyl)-5-oxocyclopentyl)-, methyl ester, (1alpha,2beta(1E,3R*),3alpha)-
Previous Indexing: Prostaglandins E, Synthetic (1978-1991)
Public MeSH Note: 92; ENPROSTIL was indexed under PROSTAGLANDINS E, SYNTHETIC 1985-91
Online Note: use ENPROSTIL (NM) to search ENPROSTIL 1985-91
History Note: 92; was ENPROSTIL (NM) 1985-91
DeCS ID: 30130
Unique ID: D016620
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1992/01/01
Date of Entry: 1991/01/25
Revision Date: 2015/06/08
Enprostil - Preferred
Concept UI M0025335
Scope note A synthetic PGE2 analog that has an inhibitory effect on gastric acid secretion, a mucoprotective effect, and a postprandial lowering effect on gastrin. It has been shown to be efficient and safe in the treatment of gastroduodenal ulcers.
Preferred term Enprostil
Enprostil, (1alpha(R*),2beta(1E,3S*),3alpha)-(+-)-Isomer - Related but not broader or narrower
Concept UI M0329475
Preferred term Enprostil, (1alpha(R*),2beta(1E,3S*),3alpha)-(+-)-Isomer
Enprostil, (1alpha,2alpha(1E,3S*),3beta)-(+-)-Isomer - Related but not broader or narrower
Concept UI M0329476
Preferred term Enprostil, (1alpha,2alpha(1E,3S*),3beta)-(+-)-Isomer
Enprostil, (1alpha,2beta(1E,3R*),3alpha)-(+-)-Isomer - Related but not broader or narrower
Concept UI M0329477
Preferred term Enprostil, (1alpha,2beta(1E,3R*),3alpha)-(+-)-Isomer
RS-84135 - Narrower
Concept UI M0351564
Preferred term RS-84135
Entry term(s) RS 84135
RS84135
Enprostil, (1R-(1alpha(S*),2beta(1E,3R*),3alpha))-Isomer - Related but not broader or narrower
Concept UI M0329479
Preferred term Enprostil, (1R-(1alpha(S*),2beta(1E,3R*),3alpha))-Isomer
Enprostil, (1R-(1alpha,2beta(1E,3R*),3alpha))-Isomer - Related but not broader or narrower
Concept UI M0329478
Preferred term Enprostil, (1R-(1alpha,2beta(1E,3R*),3alpha))-Isomer
Enprostil, (1S-(1alpha(R*),2beta(1E,3R*),3alpha))-Isomer - Related but not broader or narrower
Concept UI M0329473
Preferred term Enprostil, (1S-(1alpha(R*),2beta(1E,3R*),3alpha))-Isomer
Enprostil, (1S-(1alpha(S*),2beta(1E,3R*),3alpha))-Isomer - Related but not broader or narrower
Concept UI M0329472
Preferred term Enprostil, (1S-(1alpha(S*),2beta(1E,3R*),3alpha))-Isomer
Gardrin - Narrower
Concept UI M0351565
Preferred term Gardrin
Enprostil, (1alpha(R*),2beta(1E,3R*),3alpha)-(+-)-Isomer - Related but not broader or narrower
Concept UI M0329474
Preferred term Enprostil, (1alpha(R*),2beta(1E,3R*),3alpha)-(+-)-Isomer
Enprostil, (1R-(1(R*),2beta(1E,3R*),3alpha))-Isomer - Related but not broader or narrower
Concept UI M0329480
Preferred term Enprostil, (1R-(1(R*),2beta(1E,3R*),3alpha))-Isomer



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