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Descriptor English: Everolimus
Descriptor Spanish: Everolimus
Descriptor everólimus
Entry term(s) Zortress
everolimus
Scope note: Derivado del sirólimus y un inhibidor de la SERINA-TREONINA QUINASAS TOR. Se utiliza para prevenir el RECHAZO DE INJERTO en pacientes con trasplantes del corazón y riñón mediante el bloqueo de la señales de proliferación celular. También es un ANTINEOPLÁSICO.
Descriptor Portuguese: Everolimo
Descriptor French: Évérolimus
Entry term(s): 001, RAD
40-O-(2-hydroxyethyl)-rapamycin
Afinitor
Certican
RAD 001
RAD, SDZ
RAD001
SDZ RAD
SDZ-RAD
Zortress
Tree number(s): D02.540.505.760.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000068338
Scope note: A derivative of sirolimus and an inhibitor of TOR SERINE-THREONINE KINASES. It is used to prevent GRAFT REJECTION in heart and kidney transplant patients by blocking cell proliferation signals. It is also an ANTINEOPLASTIC AGENT.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents
Immunosuppressive Agents
Registry Number: 9HW64Q8G6G
Public MeSH Note: 2016; EVEROLIMUS was indexed under SIROLIMUS 1998-2015; and under POLYENES 1997-1998
History Note: 2016 (1997)
DeCS ID: 55896
Unique ID: D000068338
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2022/07/14
Everolimus - Preferred
Concept UI M000602394
Scope note A derivative of sirolimus and an inhibitor of TOR SERINE-THREONINE KINASES. It is used to prevent GRAFT REJECTION in heart and kidney transplant patients by blocking cell proliferation signals. It is also an ANTINEOPLASTIC AGENT.
Preferred term Everolimus
Entry term(s) 40-O-(2-hydroxyethyl)-rapamycin
RAD, SDZ
SDZ RAD
SDZ-RAD
RAD 001 - Narrower
Concept UI M0375756
Preferred term RAD 001
Entry term(s) 001, RAD
RAD001
Afinitor - Narrower
Concept UI M000603402
Preferred term Afinitor
Certican - Narrower
Concept UI M0446654
Preferred term Certican
Zortress - Narrower
Concept UI M000752918
Preferred term Zortress



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