Pesquisa sobre: KARYOPHERINS 
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Descritor Inglês:   Karyopherins 
Descritor Espanhol:   Carioferinas 
Descritor Português:   Carioferinas 
Sinônimos Inglês:   Exportins
Importin
Importins
Transportin
Transportins  
Categoria:   D12.776.157.530.750.500
D12.776.543.585.750.500
D12.776.660.502
Definição Inglês:   A family of proteins involved in NUCLEOCYTOPLASMIC TRANSPORT. Karyopherins are heteromeric molecules composed two major types of components, ALPHA KARYOPHERINS and BETA KARYOPHERINS, that function together to transport molecules through the NUCLEAR PORE COMPLEX. Several other proteins such as RAN GTP BINDING PROTEIN and CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN bind to karyopherins and participate in the transport process. 
Relacionados Inglês:   Active Transport, Cell Nucleus
 
Nota Histórica Inglês:   2002; use KARYOPHERINS (NM) 1995-2001 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   36191 
Identificador Único:   D028884 

Ocorrência na BVS:
 
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MEDLINE    
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