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Descriptor English: Lasalocid
Descriptor Spanish: Lasalocido
Descriptor lasalocido
Scope note: Antibiótico ionóforo catiónico obtenido del Streptomyces lasaliensis que, entre otros efectos, disocia los flujos de calcio en las fibras musculares. Se utiliza como coccidiostático, especialmente en aves de corral.
Descriptor Portuguese: Lasalocida
Descriptor French: Lasalocide
Entry term(s): Avatec
Lasalocid A
Ro 2 2985
Ro 2-2985
Ro 22985
X-537A
Tree number(s): D03.383.312.490
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007832
Scope note: Cationic ionophore antibiotic obtained from Streptomyces lasaliensis that, among other effects, dissociates the calcium fluxes in muscle fibers. It is used as a coccidiostat, especially in poultry.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Coccidiostats
Ionophores
Registry Number: W7V2ZZ2FWB
CAS Type 1 Name: Benzoic acid, 6-(7-(5-ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furanyl)-4-hydroxy-3,5-dimethyl-6-oxononyl)-2-hydroxy-3-methyl-, (2R-(2alpha(2S*(3R*,4S*,5S*,7R*),3S*,5S*),5alpha,6beta))-
Previous Indexing: Antibiotics (1973-1974)
Benzoates (1973-1974)
Public MeSH Note: 80; was indexed under ANTIBIOTICS 1975-79
Online Note: use LASALOCID to search X 537A 1975-77
History Note: 80(78); was see under ANTIBIOTICS 1978-79; was X 537A see under ANTIBIOTICS 1975-77
DeCS ID: 8011
Unique ID: D007832
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1980/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/05/31
Lasalocid - Preferred
Concept UI M0012243
Scope note Cationic ionophore antibiotic obtained from Streptomyces lasaliensis that, among other effects, dissociates the calcium fluxes in muscle fibers. It is used as a coccidiostat, especially in poultry.
Preferred term Lasalocid
Entry term(s) Lasalocid A
Ro 2-2985 - Narrower
Concept UI M0353165
Preferred term Ro 2-2985
Entry term(s) Ro 2 2985
Ro 22985
X-537A - Narrower
Concept UI M0361711
Preferred term X-537A
Avatec - Narrower
Concept UI M0012242
Preferred term Avatec



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