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Descriptor English: Manganese
Descriptor Spanish: Manganeso
Descriptor manganeso
Scope note: Oligoelemento que tiene por símbolo atómico Mn, número atómico 25 y peso atómico 54,94. Se concentra en las MITOCONDRIAS, principalmente en la HIPÓFISIS, HÍGADO, PÁNCREAS, RIÑÓN y HUESO, influye en la síntesis de MUCOPOLISACÁRIDOS, estimula la síntesis hepática de COLESTEROL y ÁCIDOS GRASOS y es un cofactor de muchas ENZIMAS como la ARGINASA y la FOSFATASA ALCALINA en el HÍGADO. (Traducción libre de: AMA Drug Evaluations Annual 1992, p2035).
Descriptor Portuguese: Manganês
Descriptor French: Manganèse
Tree number(s): D01.268.556.484
D01.268.956.374
D01.552.544.484
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008345
Scope note: A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DF deficiency
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Entry Combination: poisoning:Manganese Poisoning
Pharm Action: Trace Elements
Registry Number: 42Z2K6ZL8P
CAS Type 1 Name: Manganese
DeCS ID: 8517
Unique ID: D008345
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Manganese - Preferred
Concept UI M0012987
Scope note A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Preferred term Manganese



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