Pesquisa sobre: MECHLORETHAMINE 
Descritores Encontrados: 1
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Descritor Inglês:   Mechlorethamine 
Descritor Espanhol:   Mecloretamina 
Descritor Português:   Mecloretamina 
Sinônimos Inglês:   Bis(2-chloroethyl)methylamine
Caryolysine
Chlorethazine
Chlormethine
Cloramin
Embichin
Hydrochloride N-Oxide, Mechlorethamine
Hydrochloride, Mechlorethamine
Mechlorethamine Hydrochloride
Mechlorethamine Hydrochloride N Oxide
Mechlorethamine Hydrochloride N-Oxide
Mechlorethamine N Oxide
Mechlorethamine N-Oxide
Mechlorethamine Oxide
Methylchlorethamine
Mitomen
Mustargen
Mustine
N-Oxide, Mechlorethamine Hydrochloride
N-Oxide, Nitrogen Mustard
NSC 10107
NSC 762
NSC-10107
NSC-762
NSC10107
NSC762
Nitrogen Mustard
Nitrogen Mustard N Oxide
Nitrogen Mustard N-Oxide
Nitrogranulogen
Nitromin  
Categoria:   D02.455.526.728.650.529
Definição Inglês:   A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA. 
Ação Farmacológica:   Alkylating Agents
Chemical Warfare Agents
Irritants
Antineoplastic Agents, Alkylating
 
Nota Histórica Inglês:   MECHLORETHAMINE OXIDE was heading 1963-79; NITROGEN MUSTARD N-OXIDE was NITROGEN MUSTARD N-OXIDE (NM) 1984-91 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Número do Registro:   8635 
Identificador Único:   D008466 

Ocorrência na BVS:
 

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