Pesquisa sobre: MELPHALAN 
Descritores Encontrados: 1
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Descritor Inglês:   Melphalan 
Descritor Espanhol:   Melfalán 
Descritor Português:   Melfalan 
Sinônimos Inglês:   4-(Bis(2-chloroethyl)amino)phenylalanine
Alkeran
L-PAM
Medphalan
Merphalan
Mustard, Phenylalanine
Phenylalanine Mustard
Sarcolysine
Sarkolysin  
Categoria:   D02.455.526.728.650.594
D12.125.072.050.685.500
Definição Inglês:   An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen. 
Ação Farmacológica:   Antineoplastic Agents, Alkylating
Myeloablative Agonists
 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Número do Registro:   8727 
Identificador Único:   D008558 

Ocorrência na BVS:
 
LILACS    
MEDLINE    
IBECS    

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