Pesquisa sobre: MUSTARD COMPOUNDS 
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Descritor Inglês:   Mustard Compounds 
Descritor Espanhol:   Compuestos de Mostaza 
Descritor Português:   Compostos de Mostarda 
Sinônimos Inglês:   Compounds, Mustard  
Categoria:   D02.455.526.728
Definição Inglês:   Strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis(2-chloroethyl)- groups. Although otherwise structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA. They are generally highly toxic but include among their number many widely used and effective antineoplastic agents. 
Nota Histórica Inglês:   68 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Número do Registro:   21038 
Identificador Único:   D009150 

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